Systematic review of prophylactic vs rescue surfactant.
نویسنده
چکیده
Outcomes assessed in the review Neonatal mortality, total mortality, pneumothorax, pulmonary interstitial emphysema, X-ray grade at 6 hours (grades 3 to 4), number receiving oxygen at 28 days, number receiving oxygen at 36 weeks, all brain haemorrhages, intraventricular haemorrhages (grade 3 and 4), periventricular leukomalacia, patent ductus arteriosus, necrotising enterocolitis, retinopathy of prematurity.
منابع مشابه
AARC Clinical Practice Guideline. Surfactant replacement therapy: 2013.
We searched the MEDLINE, CINAHL, and Cochrane Library databases for English-language randomized controlled trials, systematic reviews, and articles investigating surfactant replacement therapy published between January 1990 and July 2012. By inspection of titles, references having no relevance to the clinical practice guideline were eliminated. The update of this clinical practice guideline is ...
متن کاملRetinopathy of prematurity in a controlled trial of prophylactic surfactant treatment.
AIMS To investigate the incidence of acute and cicatricial retinopathy of prematurity (ROP) in a cohort of premature neonates entered into a randomised, multicentre trial of prophylactic exogenous surfactant for respiratory distress syndrome (RDS) compared with controls receiving surfactant only if severe RDS developed. METHODS The incidence of acute and cicatricial ROP was assessed in 304 ne...
متن کاملTargeted early rescue surfactant in ventilated preterm infants using the click test.
OBJECTIVE To determine whether use of the click test, a rapid bedside test of surfactant function, results in earlier and more appropriate surfactant administration in ventilated preterm infants than does usual early rescue treatment. STUDY DESIGN Ventilated preterm infants (n = 126) with inspired oxygen >/=25% and mean airway pressure >/=7 cm H(2)O were randomized in gestational strata (<28 ...
متن کاملSchool-age follow-up of prophylactic versus rescue surfactant trial: pulmonary, neurodevelopmental, and educational outcomes.
BACKGROUND Exogenous surfactant replacement has improved survival and reduced pulmonary complications of prematurity. Improved early outcomes for infants of <30 weeks' gestation treated with a strategy of prophylactic versus rescue surfactant, if needed, were demonstrated in a multicenter, randomized trial conducted between 1985 and 1988. We reevaluated a subset of survivors from this trial to ...
متن کاملMortality, severe respiratory distress syndrome, and chronic lung disease of the newborn are reduced more after prophylactic than after therapeutic administration of the surfactant Curosurf.
OBJECTIVE To test the hypothesis that prophylactic treatment with the surfactant Curosurf (Chiesi Farmaceutici SPA, Parma, Italy) improves survival and respiratory problems more than rescue treatment. DESIGN Meta-analysis of three prophylaxis versus rescue treatment trials, conducted in four countries. METHODS A meta-analysis was performed with the original, individual data of mortality, se...
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ورودعنوان ژورنال:
- Archives of disease in childhood. Fetal and neonatal edition
دوره 77 1 شماره
صفحات -
تاریخ انتشار 1997